Treatment time: 45 minutes
Longevity: Up to 1 Year



Restylane® Defyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.

Restylane Defyne is an advanced HA (Hylarounic Acid) gel fillers that are approved for use in moderate to severe facial wrinkles. These next generations of dermal filler are designed using a unique manufacturing process called XpresHAn technology. XpresHAn Technology used in the HA gel of Refyne and Defyne customizes the cross-linking of the HA in the products. This allows for the creation of different gel textures to adapt to each skin texture needs, providing flexibility and support for a variety of lines, folds and areas of volume loss.  Studies show Restylane Defyne are proven to last up to 12 months.


Restylane Defyne is used to:

  • Fill in nasolabial folds, the lines that run from the corners of the nose to the corners of the mouth
  • Smooth marionette lines, the wrinkles that form between the corners of the mouth and the chin and jawline
  • Address mild-to-moderate wrinkles and folds
  • Provide facial rejuvenation in the lower face around the mout

What is the average amount I will need per treatment?

This will vary from one client to the next. On average, most clients receive 1 to 2 syringes at their visit. The common target areas would be: 

Lip Enhancement (1-2 syringes)

Nasolabial Folds (1-2 syringes)

Marionette Lines (1 syringe)




Who is a good Candidate for RESTLANE DEFYNE?

You are a candidate for a Restylane Defyne treatment if you would like to have fuller lips or are noticing wrinkles and fine lines. These signs of aging are usually caused by poor tissue support structure due to the breakdown of hyaluronic acid, fat pads, collagen, and elastin. Ideal candidates are healthy and unlikely to suffer from an allergic reaction to the treatment. 

How long will my results last?

Restylane Defyne typically lasts up to a year. Following a good skin care regimen after your treatment plays an important role in the effectiveness of any aesthetic treatment. A customized treatment plan is important for achieving the best results. This allows our healthcare professionals to tailor treatment to meet your unique needs. Book your consultation with one of our providers for your custom treatment plan.